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PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells.

Park JS, Oh Y, Park O, Foss CA, Lim SM, Jo DG, Na DH, Pomper MG, Lee KC, Lee S

J Control Release. 2017 Oct 7, 2017
Emerging Roles of Sirtuins in Ischemic Stroke.

Transl Stroke Res. 2017 Jun 27, 2017
Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke.

Fann DY, Lim YA, Cheng YL, Lok KZ, Chunduri P, Baik SH, Drummond GR, Dheen ST, Sobey CG, Jo DG, Chen CL, Arumugam TV

Mol Neurobiol. 2017 Jan 14, 2017
Dextran sulfate nanoparticles as a theranostic nanomedicine for rheumatoid arthritis.

Heo R, You DG, Um W, Choi KY, Jeon S, Park JS, Choi Y, Kwon S, Kim K, Kwon IC, Jo DG, Kang YM, Park JH

Biomaterials. 2017 Jul;131:15-26., 2017
Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke.

Balaganapathy P, Baik SH, Mallilankaraman K, Sobey CG, Jo DG, Arumugam TV

J Cereb Blood Flow Metab. 2017 Jan 1, 2017
Emerging Roles of Sirtuins in Ischemic Stroke.

She DT, Jo DG, Arumugam TV

Transl Stroke Res. 2017 Jun 27, 2017
Modelling APOE ɛ3/4 allele-associated sporadic Alzheimer's disease in an induced neuron.

Kim H, Yoo J, Shin J, Chang Y, Jung J, Jo DG, Kim J, Jang W, Lengner CJ, Kim BS, Kim J

Brain. 2017 Aug 1;140(8), 2017
Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells.

Oh Y, Park O, Swierczewska M, Hamilton JP, Park JS, Kim TH, Lim SM, Eom H, Jo DG, Lee CE, Kechrid R, Mastorakos P, Zhang C, Hahn SK, Jeon OC, Byun Y, Kim K, Hanes J, Lee KC, Pomper MG, Gao B, Lee S

Hepatology. 2016 Jul;64(1):209-23, 2016
Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation.

Song NJ, Yun UJ, Yang S, Wu C, Seo CR, Gwon AR, Baik SH, Choi Y, Choi BY, Bahn G, Kim S, Kwon SM, Park JS, Baek SH, Park TJ, Yoon K, Kim BJ, Mattson MP, Lee SJ, Jo DG, Park KW.

Sci Rep. 2016 Jan 20;6:19377, 2016
Phytochemicals in Ischemic Stroke.

Kim J, Fann DY, Seet RC, Jo DG, Mattson MP, Arumugam TV

Neuromolecular Med. 2016 Sep;18(3):283-305, 2016
In situ diselenide-crosslinked polymeric micelles for ROS-mediated anticancer drug delivery.

Deepagan VG, Kwon S, You DG, Nguyen VQ, Um W, Ko H, Lee H, Jo DG, Kang YM, Park JH.

Biomaterials. 2016 Oct;103:56-66., 2016
Vanillin attenuates negative effects of ultraviolet A on the stemness of human adipose tissue-derived mesenchymal stem cells.

Lee SY, Park SH, Kim MO, Lim I, Kang M, Oh SW, Jung K, Jo DG, Cho IH, Lee J.

Food Chem Toxicol. 2016 Oct;96:62-9., 2016
Cytotoxicity of lipid-soluble ginseng extracts is attenuated by plasma membrane redox enzyme NQO1 through maintaining redox homeostasis and delaying apoptosis in human neuroblastoma cells.

Kim HK, Son TG, Jo DG, Kim DC, Hyun DH.

Arch Pharm Res. 2016 Oct;39(10), 2016
Robust Therapeutic Efficacy of Matrix Metalloproteinase-2-Cleavable Fas-1-RGD Peptide Complex in Chronic Inflammatory Arthritis.

Nam EJ, Kang JH, Sa KH, Sung S, Park JY, Jo DG, Park JH, Kim IS, Kang YM.

PLoS One. 2016 Oct 14;11(10), 2016
FcγRIIb-SHIP2 axis links Aβ to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.

Kam TI, Park H, Gwon Y, Song S, Kim SH, Moon SW, Jo DG, Jung YK

Elife. 2016 Nov 11;5, 2016
Emerging roles of the γ-secretase-notch axis in inflammation.

Cheng YL, Choi Y, Sobey CG, Arumugam TV, Jo DG.

Pharmacol Ther. 2015 Mar;147:80-90., 2015
Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain.

Baik SH, Fane M, Park JH, Cheng YL, Yang-Wei Fann D, Yun UJ, Choi Y, Park JS, Chai BH, Park JS, Back SH, Jeong JI, Jang YJ, Bahn G, Lee JY, Li YI, Sobey CG, Uchida T, Park JH, Kim HT, Tang SC, Arumugam TV, Jo DG.

Ann Neurol. 2015 Mar;77(3):504-16., 2015
Indomethacin preconditioning induces ischemic tolerance by modifying zinc availability in the brain.

Lee JY, Oh SB, Hwang JJ, Suh N, Jo DG, Kim JS, Koh JY.

Neurobiol Dis. 2015 Sep;81:186-95., 2015
Bioreducible shell-cross-linked hyaluronic acid nanoparticles for tumor-targeted drug delivery.

Han HS, Thambi T, Choi KY, Son S, Ko H, Lee MC, Jo DG, Chae YS, Kang YM, Lee JY, Park JH.

Biomacromolecules. 2015 Feb 9;16(2):447-56., 2015
miR-195a inhibits adipocyte differentiation by targeting the preadipogenic determinator Zfp423.

Yun UJ, Song NJ, Yang DK, Kwon SM, Kim K, Kim S, Jo DG, Park WJ, Park KW, Kang H.

J Cell Biochem. 2015 Nov;116(11):2589-97., 2015
Autophagy Regulates Formation of Primary Cilia in Mefloquine-Treated Cells.

Shin JH, Bae DJ, Kim ES, Kim HB, Park SJ, Jo YK, Jo DS, Jo DG, Kim SY, Cho DH.

Biomol Ther (Seoul). 2015 Jul;23(4):327-32., 2015
Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy.

Kim MJ, Park JS, Lee SJ, Jang J, Park JS, Back SH, Bahn G, Park JH, Kang YM, Kim SH, Kwon IC, Jo DG, Kim K.

J Control Release. 2015 Oct 28;216:140-8., 2015
Recent developments in hyaluronic acid-based nanomedicine for targeted cancer treatment.

Rao NV, Yoon HY, Han HS, Ko H, Son S, Lee M, Lee H, Jo DG, Kang YM, Park JH

Expert Opin Drug Deliv. 2016 Feb;13(2):239-52., 2015
Suppression of cpn10 increases mitochondrial fission and dysfunction in neuroblastoma cells.

Park SJ, Jo DS, Shin JH, Kim ES, Jo YK, Choi ES, Seo HM, Kim SH, Hwang JJ, Jo DG, Koh JY, Cho DH.

PLoS One. 2014 Nov 12;9(11):e112130. doi: 10.1371/journal.pone.0112130. eCollection 2014., 2014
Cancer therapy using ultrahigh hydrophobic drug-loaded graphene derivatives.

Some S, Gwon AR, Hwang E, Bahn GH, Yoon Y, Kim Y, Kim SH, Bak S, Yang J, Jo DG, Lee H.

Sci Rep. 2014 Sep 10;4:6314. doi: 10.1038/srep06314., 2014
Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress.

Cheng YL, Choi Y, Seow WL, Manzanero S, Sobey CG, Jo DG*, Arumugam TV*.

Brain Res. 2014 Oct 24;1586:193-202., 2014
Hyaluronan nanoparticles bearing γ-secretase inhibitor: in vivo therapeutic effects on rheumatoid arthritis.

Heo R, Park JS, Jang HJ, Kim SH, Shin JM, Suh YD, Jeong JH, Jo DG* Park JH*

J Control Release. 2014 Oct 28;192:295-300, 2014
Adaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous system.
Lee J, Jo DG, Park D, Chung HY, Mattson MP.
Pharmacol Rev. 2014 Jul;66(3):815-68, 2014
Intermittent fasting attenuates inflammasome activity in ischemic stroke.
Fann DY, Santro T, Manzanero S, Widiapradja A, Cheng YL, Lee SY, Chunduri P, Jo DG, Stranahan AM, Mattson MP, Arumugam TV.
Exp Neurol. 2014 Jul;257:114-9., 2014
OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin.
Han J, Jung S, Jang J, Kam TI, Choi H, Kim BJ, Nah J, Jo DG, Nakagawa T, Nishimura M, Jung YK.
Cell Mol Life Sci. 2014 Jul;71(13):2561-76., 2014
A hyaluronic acid-methotrexate conjugate for targeted therapy of rheumatoid arthritis.
Shin JM, Kim SH, Thambi T, You DG, Jeon J, Lee JO, Chung BY, Jo DG*, Park JH*.
Chem Commun (Camb). 2014 Jun 19;50(57):7632-5., 2014
Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques.
Shin MK, Kim HG, Baek SH, Jung WR, Park DI, Park JS, Jo DG, Kim KL.
Neurobiol Aging.2014 May;35(5):990-1001., 2014
Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine.
Kim NW, Lee MS, Kim KR, Lee JE, Lee K, Park JS, Matsumoto Y, Jo DG, Lee H, Lee DS, Jeong JH.
J Control Release. 2014 Apr 10;179:11-7., 2014
Tissue plasminogen activator arrests Alzheimer's disease pathogenesis.
Oh SB, Byun CJ, Yun JH, Jo DG, Carmeliet P, Koh JY, Lee JY.
Neurobiol Aging. 2014 Mar;35(3):511-9., 2014
Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling.
Seo CR, Yang DK, Song NJ, Yun UJ, Gwon AR, Jo DG, Cho JY, Yoon K, Ahn JY, Nho CW, Park WJ, Yang SY, Park KW.
Food Chem Toxicol. 2014 Feb;64:217-24, 2014
Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery.
Thambi T, Deepagan VG, Yoon HY, Han HS, Kim SH, Son S, Jo DG, Ahn CH, Suh YD, Kim K, Kwon IC, Lee DS, Park JH.
Biomaterials. 2014 Feb;35(5):1735-43, 2014
TNF-alpha Gene Silencing Using Polymerized siRNA/Thiolated Glycol Chitosan Nanoparticles for Rheumatoid Arthritis.
Lee SJ, Lee A, Hwang SR, Park JS, Jang J, Huh MS, Jo DG, Yoon SY, Byun Y, Kim SH, Kwon IC, Youn I, Kim K.
Mol Ther. 2014 Feb;22(2):397-408, 2014
Evidence that Collaboration between HIF-1α and Notch-1 Promotes Neuronal Cell Death in Ischemic Stroke.
Cheng YL, Park JS, Manzanero S, Choi Y, Baik SH, Okun E, Gelderblom M, Fann DY, Magnus T, Launikonis BS, Mattson MP, Sobey CG, Jo DG*, Arumugam TV*,
Neurobiol Dis. 2014 Feb;62:286-95., 2014
Down-regulation of mortalin exacerbates Aβ-mediated mitochondrial fragmentation and dysfunction.
Park SJ, Shin JH, Jeong JI, Song JH, Jo YK, Kim ES, Lee EH, Hwang JJ, Lee EK, Chung SJ, Koh JY, Jo DG, Cho DH.
J Biol Chem. 2014 Jan 24;289(4):2195-204, 2014
Inhibition of Notch signalling ameliorates experimental inflammatory arthritis.
Park JS, Kim SH, Kim K, Jin CH, Choi KY, Jang J, Choi Y, Gwon AR, Baik SH, Yun UJ, Chae SY, Lee S, Kang YM, Lee KC, Arumugam TV, Mattson MP, Park JH, Jo DG*
Ann Rheum Dis. 2013 Nov 19. doi: 10.1136/annrheumdis-2013-203467. [Epub ahead of print], 2013
Evidence for a detrimental role of TLR8 in ischemic stroke.
Tang SC, Yeh SJ, Li YI, Wang YC, Baik SH, Santro T, Widiapradja A, Manzanero S, Sobey CG, Jo DG, Arumugam TV, Jeng JS.
Exp Neurol. 2013 Dec;250C:341-347. doi: 10.1016/j.expneurol.2013.10.012. Epub 2013 Oct 24., 2013
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.
Yang-Wei Fann D, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, Bernreuther C, Glatzel M, Cheng YL, Thundyil J, Widiapradja A, Lok KZ, Foo SL, Wang YC, Li YI, Drummond GR, Basta M, Magnus T, Jo DG, Mattson MP, Sobey CG, Arumugam TV.
Cell Death Dis. 2013 Sep 5;4:e790., 2013
Self-assembled dextran sulphate nanoparticles for targeting rheumatoid arthritis. Kim SH, Kim JH, You DG, Saravanakumar G, Yoon HY, Choi KY, Thambi T, Deepagan VG, Jo DG*, Park JH*.
Chem Commun (Camb). 2013 Oct 10;49(88):10349-51. (Cover story), 2013
Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo. Kim TH, Swierczewska M, Oh Y, Kim A, Jo DG, Park JH, Byun Y, Sadegh-Nasseri S, Pomper MG, Lee KC, Lee S.
Angew Chem Int Ed Engl. 2013 Jul 1;52(27):6880-4., 2013
Calsenilin Contributes to Neuronal Cell Death in Ischemic Stroke. Park JS, Manzanero S, Chang JW, Choi Y, Baik SH, Cheng YL, Li YI, Gwon AR, Woo HN, Jang J, Choi IY, Lee JY, Jung YK, Tang SC, Sobey CG, Arumugam TV, Jo DG*.
Brain Pathol. 2013 Jul;23(4):402-12., 2013
Silk proteins stimulate osteoblast differentiation by suppressing the Notch signaling pathway in mesenchymal stem cells.Jung SR, Song NJ, Yang DK, Cho YJ, Kim BJ, Hong JW, Yun UJ, Jo DG, Lee YM, Choi SY, Park KW.
Nutr Res. 2013 Feb;33(2):162-70., 2013
Evidence That the EphA2 Receptor Exacerbates Ischemic Brain Injury. Thundyil J, Manzanero S, Pavlovski D, Cully TR, Lok KZ, Widiapradja A, Chunduri P, Jo DG, Naruse C, Asano M, Launikonis BS, Sobey CG, Coulthard MG, Arumugam TV.
PLoS One. 2013;8(1):e53528. doi: 10.1371/journal.pone.0053528. Epub 2013 Jan 7., 2013
Molecular chaperone-like hyaluronic acid nanoparticles: Implications as the carrier for protein delivery systems. Maharajan Sivasubramanian, Ah Reum Kang, Hwa Seung Han, Roun Heo, Joon-Youl Lee, Kap Jin Kim, Sang Min Jeon, Su Young Chae, Dong-Gyu Jo, Jong-Ho Kim,Jae Hyung Park.
Macromolecular Research 2012; 20:1007-1010., 2012
Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease. Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE 3rd, Bernier M, Lee J, Markesbery WR, Mattson MP, Jo DG*.
Aging Cell. 2012 Aug;11(4):559-568.(Cover stroy), 2012
Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways. Widiapradja A, Vegh V, Lok KZ, Manzanero S, Thundyil J, Gelderblom M, Cheng YL, Pavlovski D, Tang SC, Jo DG, Magnus T, Chan SL, Sobey CG, Reutens D, Basta M, Mattson MP, Arumugam TV.
J Neurochem. 2012 Jul; 122: 321-32., 2012
Polysaccharide-based nanoparticles: a versatile platform for drug delivery and biomedical imaging. Saravanakumar G, Jo DG, Park JH. Curr Med Chem. 2012 Jul 1;19(19):3212-29., 2012
Thiolated Glycol Chitosan Bearing alpha-Cyclodextrin for Sustained Delivery of PEGylated Human Growth Hormone.Maharajan S, Kim YJ, Chae SY, Son S, Jo DG, Lee KC, Yoo CK, Park JH.
J. Biomat. Sci. Pol. Ed. 2012; 23: 1995-2005, 2012
Gong EJ, Park HR, Kim ME, Piao S, Lee E, Jo DG, Chung HY, Ha NC, Mattson MP, Lee J (2011) Morin attenuates tau hyperphosphorylation by inhibiting GSK3β. Neurobiol. Dis. 44, 223-230, 2011
Wei Z, Chigurupati S, Arumugam TV, Jo DG, Li H, Chan SL (2011) Notch activation enhances the microglia-mediated inflammatory response associated focal cerebral ischemia. Stroke 42, 2589-2594, 2011
Arumugam TV, Cheng YL, Choi Y, Choi YH, Yang S, Yun YK, Park JS, Yang DK, Thundyil J, Gelderblom M, Karamyan VT, Tang SC, Chan SL, Magnus T, Sobey CG, Jo DG (2011) Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke. Mol. Pharmacol. 80, 23-31, 2011
Jung SR, Kim YJ, Gwon AR, Lee J, Jo DG, Jeon TJ, Hong JW, Park KM, Park KW (2011) Genistein Mediates the Anti-Adipogenic Actions of Sophora japonica L. Extracts. J. Med. Food 44, 135-139, 2011
Kim SR, Jeong HY, Yang S, Choi SP, Seo MY, Yun YK, Choi Y, Baik SH, Park JS, Gwon AR, Yang DK, Lee CH, Lee SM, Park KW, Jo DG (2011) Effects of chronic alcohol consumption on expression levels of APP and Aβ-producing enzymes. BMB Rep. 44, 135-139, 2011
Woo HN, Baik SH, Park JS, Gwon AR, Yang S, Yun YK, Jo DG (2011) Secretases as therapeutic targets for Alzheimer's disease. Biochem. Biophys. Res. Commun. 404, 10-15, 2011
Thundyil J, Tang SC, Okun E, Shah K, Karamyan VT, Li YI, Woodruff TM, Taylor SM, Jo DG, Mattson MP, Arumugam TV (2010) Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Exp Transl Stroke Med. 2, 15, 2010
Kim YJ, Chae SY, Jin CH, Sivasubramanian M, Son S, Choi KY, Jo DG, Kim K, Kwon IC, Lee KC & Park JH (2010) Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis. Biomaterials 31, 9057-9064, 2010
Chae SY, Kim TH, Park K, Jin CH, Son S, Lee S,Youn YS, Kim K, Jo DG, Kwon IC, Chen X, Lee KC (2010) Improved antitumor activity and tumor targeting of N-terminal specific PEGylated tumor necrosis factor-related apoptosis inducing ligand. Mol. Cancer Ther. 9, 1719-1729, 2010
Jo DG, Arumugam TV, Woo HN, Park JS, Tang SC, Mughal M, Hyun DH, Park JH, Choi YH, Gwon AR, Camandola S, Chen A, Cai H, Song W, Markesbery WR, Mattson MP (2010) Evidence that γ-Secretase Mediates Oxidative Stress-Induced ß-Secretase Expression in Alzheimer’s Disease. Neurobiology of Aging 31, 917-925, 2010
Choi YH, Gwon AR, Jeong HY, Park JS, Baik SH, Arumugam TV, Jo DG (2010) Contribution of gamma-secretase to calcium-mediated cell death. Neurosci. Lett. 469, 425-428, 2010
Gwon AR, Park JS, Park JH, Baik SH, Jeong HY, Hyun DH, Park KW, Jo DG (2010) Selenium attenuates A beta production and A beta-induced neuronal death. Neurosci. Lett. 469, 391-395, 2010
Jin CH, Chae SY, Lee EY, Song YW, Yang HK, Jo DG, Lee KC (2010) Effect of TNF-Related Apoptosis-Inducing Ligand (TRAIL) on the Reduction of Joint Inflammation in Experimental Rheumatoid Arthritis. J. Pharmacol. Exp. Ther. 332, 858-865, 2010
Woo HN, Park JS, Gwon AR, Arumugam TV, Jo DG (2009) Alzheimer’s disease and Notch signaling. Biochem. Biophys. Res. Commun. 390, 391-395, 2009
Pyo JO, Nah J, Kim HJ, Chang JW, Song YW, Yang DK, Jo DG, Kim HR, Chae HJ, Chae SW, Hwang SY, Kim SJ, Kim HJ, Cho C, Oh CG, Park WJ, Jung YK (2008) Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice. J. Biol. Chem. 283, 30707-30714, 2008
Woo HN, Chang JW, Choi YH, Gwon AR, Jung YK, Jo DG (2008) Characterization of subcellular localization and Ca2+ modulation of calsenilin/DREAM/KChIP3. NeuroReport 19, 1193-1197, 2008
Kyriazis GA, Wei Z, Vandermey M, Jo DG, Xin O, Mattson MP, Chan SL (2008) Numb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesis. J. Biol. Chem. 283, 25492-25502, 2008
Tang SC, Lathia JD, Selvaraj PK, Jo DG, Mughal MR, Cheng A, Siler DA, Markesbery WR, Arumugam TV, Mattson MP. (2008) Toll-Like Receptor-4 Mediates Neuronal Apoptosis Induced by Amyloid β-Peptide and the Membrane Lipid Peroxidation Product 4-Hydroxynonenal. Experimental Neurology 213, 25492-25502, 2008
Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M (2008) Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J. Neurochem. 104, 683-695, 2008
Chigurupati S, Arumugam TV, Son TG, Lathia JD, Jameel S, Mughal MR, Tang SC, Jo DG, Camandola S, Giunta M, Rakova I, McDonnell N, Miele L, Mattson MP, Poosala S (2007) Involvement of notch signaling in wound healing. PLoS ONE 2, e1167, 2007
Arumugam TV, Tang SC, Lathia JD, Cheng A, Mughal MR, Chigurupati S, Magnus T, Chan SL, Jo DG, Ouyang X, Fairlie DP, Granger DN, Vortmeyer A, Basta M, Mattson MP (2007) Intravenous Immunoglobulin (IVIG) Protects the Brain Against Experimental Stroke by Preventing Complement-Mediated Neuronal Cell Death. Proc. Natl. Acad. Sci. U. S. A. 104, 14104-14109, 2007
Weissman L, Jo DG, Soerensen M, Sopuza-Pinto N, Markesbery WR, Mattson MP, Bohr V (2007) Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment. Nucleic Acids Res. 35, 5545-5555, 2007
Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG, Lathia JD, Siler DA, Chigurupati S, Ouyang X, Magnus T, Camandola S, Mattson MP (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 13798-13803, 2007
Tang SC, Arumugam TV, Cutler RG, Jo DG, Magnus T, Chan SL, Mughal MR, Telljohann RS, Nassar M, Ouyang X, Calderan A, Ruzza P, Guiotto A & Mattson MP (2007) Neuroprotective actions of a histidine analogue in models of ischemic stroke. J. Neurochem. 101, 729-736, 2007
Cheng A, Arumugam TV, Liu D, Khatri RG, Mustafa K, Kwak S, Ling HP, Gonzales C, Xin O, Jo DG, Guo Z, Mark RJ & Mattson MP (2007) Pancortin-2 interacts with WAVE1 and Bcl-xL in a mitochondria-associated protein complex that mediates ischemic neuronal death. J. Neurosci. 27, 1519-1528, 2007
Chang JW, Choi H, Kim HJ, Jo DG, Jeon YJ, Noh JY, Park WJ & Jung YK (2007) Neuronal vulnerability of CLN3 deletion to calcium-induced cytotoxicity is mediated by calsenilin. Hum. Mol. Genet. 16, 317-326, 2007
Hyun DH, Emerson SS, Jo DG, Mattson MP & de Cabo R (2007) Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging. Proc. Natl. Acad. Sci. U. S. A. 103, 19908-19912, 2007
Arumugam T*, Chan S*,Jo DG*, Yilmaz G, Tang SC, Cheng A, Gleichmann M, Okun E, Dixit VD, Chigurupati S, Mughal MR, Ouyang X, Miele L, Magnus T, Poosala S, Granger DN, & Mattson MP (2006) Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. Nature Medicine 12, 621-623 (*equal contribution), 2006
Mattson MP, Cutler RG & Jo DG (2005) Alzheimer peptides perturb lipid-regulating enzymes. Nature Cell Biology 7, 1045-1047, 2005
Guiotto A, Calderan A, Ruzza P, Osler A, Rubini C, Jo DG, Mattson MP & Borin G (2005) Synthesis and evaluation of neuroprotective alpha,beta-unsaturated aldehyde scavenger histidyl-containing analogues of carnosine. J. Med. Chem. 48, 6156 -6161, 2005
Hasegawa T, Ukai W, Jo DG, Xu X, Mattson MP, Nakagawa M, Araki W, Saito T & Yamada T (2005) Homocysteic Acid Induces Intraneuronal Accumulation of Neurotoxic Aβ42: Implications for the Pathogenesis of Alzheimer’s Disease. J. Neurosci. Res. 80, 869-876, 2005
Jo DG, Jang J, Kim B, Lundkvist J & Jung YK (2005) Overexpression of calsenilin enhances gamma-secretase activity. Neurosi. Lett. 378, 59-64, 2005
Woo HN, Hong G, Jun J, Cho D, Choi H, Lee H, Chung C, Kim I, Jo DG, Pyo J, Bertin J & Jung YK (2004) Inhibition of Bcl10-mediated activation of NF-kappa B by BinCARD, a Bcl10-interacting CARD protein. FEBS Lett. 578, 239-244, 2004
Jo DG, Jun J, Chang J, Hong Y, Song S, Cho D, Shim S, Lee H, Cho C, Kim D & Jung YK (2004) Calcium Binding ARC Mediates Regulation of Caspase-8 and Cell Death. Mol. Cell. Biol. 24, 9763-9770, 2004
Jo DG, Lee J, Hong Y, Song, S, Mook-Jung I, Koh J, Jung YK (2004) Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer’s disease and cultured neurons after amyloid-ß exposure. J. Neurochem. 88, 604-611, 2004
Song S, Kim S, Hong Y, Jo DG, Lee J, Shim S, Chung C, Yates, A, Ichijo H & Jung YK (2003) Essential role of E2-25K/Hip-2 in the neurotoxicity of amyloid-b and UBB+1 in Alzheimer’s disease. Molecular Cell 12, 553-563, 2003
Jo DG, Chang JW, Hong H, Mook-Jung I & Jung YK (2003) Contribution of presenilin/γ-secretase to calsenilin-mediated apoptosis Biochem. Biophys. Res. Commun. 305, 62-66., 2003
Hong YM, Jo DG, Lee J, Chang J, Nam J, Noh J, Koh J & Jung YK (2003) Down-regulation of ARC Contributes to Vulnerability of Hippocampal Neurons to Ischemia/Hypoxia. FEBS Lett. 543, 170-173, 2003
Hong YM, Jo DG, Kim S, Lee M & Jung, YK (2003) Reduced expression of calsenilin/DREAM/KChIP3 in the brains of kainic acid-induced seizure and epilepsy patients. Neurosci. Lett 340, 33-36, 2003
Kim MJ, Jo DG, Hong G, Kim B, Lai M, Cho D, Kim K, Bandyopadhyay A, Hong Y, Kim D, Cho C, Liu J, Snyder S & Jung YK (2002) Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death. Proc. Natl. Acad. Sci. USA 99, 9870-9875., 2002
Kim KW, Kim BJ, Chung CW, Jo DG, Kim I, Song Y, Kwon Y, Woo H & Jung YK (2002) Caspase cleavage product lacking amino-terminus of IkBa sensitizes resistant cells to TNF-alpha and TRAIL-induced apoptosis. J. Cell. Biochem. 85, 334-345, 2002
Jo DG, Kim M, Choi Y, Kim I, Song Y, Woo H, Chung C & Jung YK (2001) Pro-apoptotic function of calsenilin/DREAM/KChIP3. FASEB J. 15, 589-591, 2001
Jo DG, Lyu M, Cho E, Park D, Kozak C & Kim MG (2001) Identification and genetic mapping of the mouse Fkbp9 gene encoding a new member of FK506-binding protein family. Mol. Cells 12, 272-275, 2001
Kim KW, Chung H, Chung C, Kim I, Miura M, Wang S, Zhu H, Moon K, Rha G, Park J, Jo DG, Woo H, Song Y, Kim B, Yuan J & Jung YK (2001) Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis. Oncogene 18, 358-366, 2001
Chung CW, Song Y, Kim I, Yoon W, Ryu B, Jo DG, Woo H, Kwon Y, Kim H, Gwag B, Mook-Jung I & Jung YK (2001) Proapoptotic effects of tau cleavage product generated by caspase-3. Neurobiol. Dis. 8,162-172, 2001
Kim H, Jung YK, Jo DG & Park SH (2000) Assignment of the rat calcineurin inhibitor gene (Cain) to rat chromosome band 20p12 by fluorescence in situ hybridization. Cytogenet. Cell Genet. 89,236-237, 2000
Chung CW, Kim IK, Kim H, Jo DG, Song YH, Woo H & Jung YK (1998) Cloning and characterization of cell death modulator genes of ICE/CED-3 family. Proc. Mol. Biol. Genet. 13: 483-485, 1998
Jo DG & Jung YK (1998) Apoptosis: activation of caspase. Curr. Cell. Biol. 3: 3-17, 1998
Oh W, Yoo J, Jo D, Song YH, Kim MG & Park D (1997) Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion. Biochem. Biophys. Res. Commun. 235:794-798, 1997
Jo DG (July 9, 2011) Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the NFkB-Bim pathway in ischemic stroke. The 21st International Conference of the Korean Society for Gerontology: Intervention of Aging and Age-related Diseases (Grand Ballroom, Hotel Nongshim, Busan, Korea), 2011
Jo DG (May 20, 2011) Roles of gamma-secretase in Alzheimer’s disease and other diseases. 2011 Drug Development consortium (DDC) (National Cancer Center, Korea), 2011
Jo DG (Mar 11, 2011) Gamma-secretase as a therapeutic target for Alzheimer’s disease and other diseases. Symposium for Cellular Network Research by Bio-Physical Approaches (Yonsei University, Korea), 2011
Jo DG (Dec 18, 2009) Oxidative lipid modification of gamma-secretase enhances Abeta production in Alzheimer's disease. 2009 The Korean Society for Neurodegenerative Disease Meeting (HIT center, Seoul, Korea), 2009
Jo DG (June, 2009) γ-secretase mediates oxidative stress-induced expression of γ-secretase resulting in Aβ production of Azheimer’s disease. The 32th National Meeting of the Japan Society for Biomedical Gerontology (Yokohama, Japan), 2009
Jo DG (November 15, 2008) Lipid peroxidation product 4-hyroxynonenal modifies gamma-secretase activity in Alzheimer’s disease. BLSA conference 2008 (Baltimore, MD, USA), 2008
Jo DG (May 15- May 16, 2008) Oxidative lipid modification of γ-secretase and Aβ production in Alzheimer’s disease. The 8th Korea-Japan Gerontologist Joint Meeting (Daegu, Korea), 2008
Jo DG, Mattson MP (Oct 13-Oct 18, 2006) Oxidative stress regulates γ-secretase dependent β-secretase expression. 2006 Society For Neuroscience (Atlanta, USA), 2006
Jo DG, Mattson MP (Mar 29-Mar 31, 2006) Secretases in Alzheimer’s disease. 11th Annual NIA Intramural Retreat (MD, USA), 2006
Jo DG, Mattson MP (Mar 30-Apr 1, 2005) The role of membrane lipid peroxidation in amyloidogenic APP processing. 10th Annual NIA Intramural Retreat (MD, USA), 2005
Jo DG, Lee JY, Hong YM, Mook-Jung I, Koh JY, Jung YK (2003) Functional coordination of calsenilin and presenilin/γ-secretase in the pathogenesis of Alzheimer’s disease. The Korea Society for Molecular and Cellular Biology (Seoul, Korea), 2003
Jo DG, Jung YK (2001) Pro-apoptotic and amyloidogenic fuction of calsenilin/DREAM/KChIP3. The Biochemical Society of the Republic of Korea (Seoul, Korea), 2001
Jo DG, Hong YM, Jung YK (October 11-12, 2001) Role of calsenilin/DREAM/KChIP3 in neurodegenerative disease. The 13th Annual Meeting of the Korean Society for Molecular and Cellular Biology (Seoul, Korea), 2001
약품생화학실험, 도서출판신일북스, 총187면, 2011-02 발행, ISBN: 978-89-5702-257-3, 2011
건강전문직을 위한 약리학, 포널스출판사, 총472면 [역서], 2010-09 발행, ISBN: 978-89-93599-44-2, 2010